C3b deposition assay
The C3b deposition assay is a laboratory technique used to evaluate the activation of the complement system, specifically measuring the deposition of complement component C3b on cell surfaces or particles. This assay helps in assessing how the complement pathways, particularly the alternative pathway, contribute to immune responses. By quantifying C3b deposition, researchers can study the mechanisms of opsonization, understand disease processes involving the complement system, and explore potential therapeutic strategies targeting complement activation.
